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Thursday, August 23, 2012
Wednesday, August 22, 2012
Samsung Galaxy Reverb hands-on
We're live in New York tonight where Samsung is teaming with Boost and Virgin Mobile to announce a bevy of new devices to flood the prepaid market in the coming weeks. First up is the Samsung Galaxy Reverb, a remarkably handsome little device that'll be available for preorder on Virgin Mobile starting on August 29. For $249.99 you'll get a 4-inch WVGA display (it looks great), a 5 MP camera, 4 GB of internal storage, and a 1.4 Ghz single-core processor. It's relatively thin and light at 128.7 grams and 11.30 mm thick, and it will run on Virgin's 3G EVDO Rev A network.
For a prepaid "budget" device, the Reverb is certainly packing a punch with that processor, and speeding through the homescreens felt fluid and smooth. The Reverb will thankfully ship with Ice Cream Sandwich, skinned with a TouchWiz that's not too different from just about every other recent Galaxy device. We'll put it through its paces in the coming weeks, but until then, you can check out our shots from this dimly lit bar below. The Reverb will hit shelves in mid-September.
 |  |
Source: http://feedproxy.google.com/~r/androidcentral/~3/PReE-FHMvwI/story01.htm
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Essex Police ? IPCC find ?Failures? re Domestic Violence | Tina Royles
The Independenant Police Complaints Commission has today issued their report following their investigation into a Domestic Violence Case in Essex which resulted in a ?Double Murder? Investigation.
The Case in which the IPCC are refering to is the murder of Christine Chambers and her daughter Shania who were shot by David Oakes on 06th June 2011. Oakes was Chambers ex partner and the father of Shania.
Although it has been highlighted by Christine?s father in news reports that the Murder Investigation Team were supportive and did a good job; he and the report have highlighted more could have been done in the run up to the double murder in the previous incidents of domestic violence reported to Essex Police.
Whilst Essex Police?s Assistant Chief Constable Maurice Mason has in news reports today stated the force has introduced 76 new posts in the Public Protection Team (Which oversee?s Vulnerable People including Domestic Violence), and also introduced a dedicated Domestic Abuse Intelligence Team; all which are positive steps, the IPCC Commissioner Rachel Cerfontyne in the report has made recommendations such as a Process of Sharing Information between forces and agencies such as Social Services, Courts, Solicitors (In particular Child Custody Proceedings). Others failures highlighted were:
Lack of Adequate Training
Insufficient Resources allocated to Domestic Violence Cases
Poor Oversight
Failure of Police Systems
So why apart from the obvious as in its a Domestic Violence Issue am I raising it here?
From 1990 ? 2006 I was a Police Officer within Essex Police; spending my first five years?at Braintree where the double murder happened, I transferred to Harlow Division in 1995; where I became heavily involved in dealing with Domestic Violence; first as an DV `Expert` on the response shift, and then moving into the role of Domestic Violence Officer. I spent the majority of my career as the Domestic Violence Officer, and was a driving force within Essex Police in putting Domestic Violence on the `map` or `radar`. I was a Chair of a forward thinking Domestic Violence Forum pushing forward key projects and initiative to help all involved in Domestic Violence.? As the Domestic Violence Officer I implemented many key strategies which were implemented forcewide, and held groundbreaking conferences to raise awareness of domestic violence. I compiled and delivered training for The Essex Magistrates Association which was provided for all Essex Magistrates which was thought so useful Domestic Violence training is delivered on a rolling programme for all Magistrates, I also delivered domestic violence training for many other key agencies on a local and Essex wide basis.
I?was recognised by the then Chief Constable David Stevens to be a driving force and instrumental in work around Domestic Violence forming DV monitoring groups, organising publicity launches, raising the profile of Essex Police, leading to a significant increase in reported incidents, and introducing successful repeat victim/offender strategies, in particular reference was made to the fact that my professionalism, and my dedication, not only brought credit to myself but to Essex Police. I was then sent on his behalf and included in key meetings and training on domestic violence on a countywide and national basis..
I left Essex Police in 2006, and have continued working in the field of Domestic Violence, within a forum environment meeting the government targets on domestic violence, as a manager of a domestic violence perpetrator programme, but have continued to broaden my practioner and strategic knowledge and experiece within domestic violence. I have added to this substantial academic experience and knowledge in this field and also with relationships, continuing to develop and deliver tailor made training around domestic violence for professionals, and providing consultancy.
I continue to also provide `hands on` work through my therapy private practice: Selyor Therapy Centre?which?specifically involves?domestic violence counselling, and relationship counselling.
This wide ranging and unique experience and knowledge has meant my comments have been sought on both a national and international level on domestic violence cases highlighted in the press.
With all my experience and knowledge both previously internally and externally to Essex Police it saddens me to hear of their failings, and feel that they have taken a step backwards, it is?also that another incident has occured in which a fatalily has happened. Despite improvements sadly it wont be the last incident that is a serious one or indeed a fatality, and that applies to any force or agency that has dealings with the area of domestic violence.
For any agency or Police Force (In particular Essex Police) that would like consultancy or training on Domestic Violence please contact me through either of my websites.
Also for victims/survivors of domestic violence, or family members trying to move forward with their lives after a domestic violence experience then again contact with me can be made through the below websites.
www.tinaroyles.com?? or? www.selyortherapycentre.com
For the stories in the National Newspapers refering to the above case in Essex please see the below links:
http://news.uk.msn.com/uk/police-apology-over-double-murder
http://www.guardian.co.uk/uk/2012/aug/22/police-failed-woman-david-oakes-ipcc?newsfeed=true
http://www.bbc.co.uk/news/uk-england-essex-19341246
http://www.telegraph.co.uk/news/uknews/crime/9492030/David-Oakes-murders-IPCC-finds-systematic-police-failings.html
http://www.itv.com/news/anglia/2012-08-22/essex-police-significant-action-taken-over-domestic-violence/
Source: http://www.tinaroyles.com/essex-police-ipcc-find-failures-re-domestic-violence
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Tuesday, August 21, 2012
Americans tune out Afghan war as fighting rages on
FILE - In this Saturday, Sept. 10, 2011 file photo, President Barack Obama looks out over graves in Section 60 at Arlington National Cemetery in Arlington, Va., where he paid his respects to those who have made the ultimate sacrifice in the past decade. It was once President Barack Obama's "war of necessity." Now, it's America's forgotten war. The Afghan conflict generates barely a whisper on the U.S. presidential campaign trail. It's not a hot topic at the office water cooler or in the halls of Congress _ even though 88,000 American troops are still fighting here and dying at a rate of one a day.(AP Photo/Carolyn Kaster, File)
FILE - In this Saturday, Sept. 10, 2011 file photo, President Barack Obama looks out over graves in Section 60 at Arlington National Cemetery in Arlington, Va., where he paid his respects to those who have made the ultimate sacrifice in the past decade. It was once President Barack Obama's "war of necessity." Now, it's America's forgotten war. The Afghan conflict generates barely a whisper on the U.S. presidential campaign trail. It's not a hot topic at the office water cooler or in the halls of Congress _ even though 88,000 American troops are still fighting here and dying at a rate of one a day.(AP Photo/Carolyn Kaster, File)
FILE - In this Wednesday, June 6, 2012 file photo, Afghan villagers gather near a house destroyed in an apparent NATO raid in Logar province, south of Kabul, Afghanistan. It was once President Barack Obama's "war of necessity." Now, it's America's forgotten war. The Afghan conflict generates barely a whisper on the U.S. presidential campaign trail. It's not a hot topic at the office water cooler or in the halls of Congress _ even though 88,000 American troops are still fighting here and dying at a rate of one a day. (AP Photo/Ihsanullah Majroh, File)
FILE -In this June 24, 2011 file photo, Canadian Forces soldier, Cpl. Ben Vandandaigue, plays on a drum kit on Forward Operating Base Sperwan Ghar overlooking the Panjwaii district of Kandahar province, Afghanistan. It was once President Barack Obama's "war of necessity." Now, it's America's forgotten war. The Afghan conflict generates barely a whisper on the U.S. presidential campaign trail. It's not a hot topic at the office water cooler or in the halls of Congress _ even though 88,000 American troops are still fighting here and dying at a rate of one a day.(AP Photo/David Goldman, File)
FILE - In this Wednesday, Aug. 15, 2012 file photo, Afghans carry a wounded woman from the scene of an explosion in Herat, west of Kabul, Afghanistan. It was once President Barack Obama's "war of necessity." Now, it's America's forgotten war. The Afghan conflict generates barely a whisper on the U.S. presidential campaign trail. It's not a hot topic at the office water cooler or in the halls of Congress _ even though 88,000 American troops are still fighting here and dying at a rate of one a day. (AP Photo/Hoshang Hashimi, File)
FILE - In this Monday, April 2, 2012 file photo, Nicholas Weichel, son of Rhode Island National Guard Sgt. Dennis Weichel Jr., who was killed in Afghanistan, stands next to his father's casket during funeral services at the state Veterans Cemetery in Exeter, R.I.. Weichel Jr., was struck and killed by an armored vehicle March 22 in Afghanistan while saving an Afghan boy. It was once President Barack Obama's "war of necessity." Now, it's America's forgotten war. The Afghan conflict generates barely a whisper on the U.S. presidential campaign trail. It's not a hot topic at the office water cooler or in the halls of Congress _ even though 88,000 American troops are still fighting here and dying at a rate of one a day.(AP Photo/Stew Milne, File)
KABUL, Afghanistan (AP) ? It was once President Barack Obama's "war of necessity." Now, it's America's forgotten war.
The Afghan conflict generates barely a whisper on the U.S. presidential campaign trail. It's not a hot topic at the office water cooler or in the halls of Congress ? even though more than 80,000 American troops are still fighting here and dying at a rate of one a day.
Americans show more interest in the economy and taxes than the latest suicide bombings in a different, distant land. They're more tuned in to the political ad war playing out on television than the deadly fight still raging against the Taliban. Earlier this month, protesters at the Iowa State Fair chanted "Stop the war!" They were referring to one purportedly being waged against the middle class.
By the time voters go to the polls Nov. 6 to choose between Obama and presumptive Republican nominee Mitt Romney, the war will be in its 12th year. For most Americans, that's long enough.
Public opinion remains largely negative toward the war, with 66 percent opposed to it and just 27 percent in favor in a May AP-GfK poll. More recently, a Quinnipiac University poll found that 60 percent of registered voters felt the U.S. should no longer be involved in Afghanistan. Just 31 percent said the U.S. is doing the right thing by fighting there now.
Not since the Korean War of the early 1950s ? a much shorter but more intense fight ? has an armed conflict involving America's sons and daughters captured so little public attention.
"We're bored with it," said Matthew Farwell, who served in the U.S. Army for five years including 16 months in eastern Afghanistan, where he sometimes received letters from grade school students addressed to the brave Marines in Iraq ? the wrong war.
"We all laugh about how no one really cares," he said. "All the 'support the troops' stuff is bumper sticker deep."
Farwell, 29, who is now studying at the University of Virginia, said the war is rarely a topic of conversation on campus ? and he isn't surprised that it's not discussed much on the campaign trail.
"No one understands how to extricate ourselves from the mess we have made there," he said. "So from a purely political point of view, I wouldn't be talking about it if I were Barack Obama or Mitt Romney either."
Ignoring the Afghan war, though, doesn't make it go away.
More than 1,950 Americans have died in Afghanistan and thousands more have been wounded since President George W. Bush launched attacks on Oct. 7, 2001 to rout al-Qaida after it used Afghanistan to train recruits and plot the Sept. 11 attacks that killed nearly 3,000 Americans.
The war drags on even though al-Qaida has been largely driven out of Afghanistan and its charismatic leader Osama bin Laden is dead ? slain in a U.S. raid on his Pakistani hideout last year.
Strangely, Afghanistan never seemed to grab the same degree of public and media attention as the war in Iraq, which Obama opposed as a "war of choice."
Unlike Iraq, victory in Afghanistan seemed to come quickly. Kabul fell within weeks of the U.S. invasion in October 2001. The hardline Taliban regime was toppled with few U.S. casualties.
But the Bush administration's shift toward war with Iraq left the Western powers without enough resources on the ground, so by 2006 the Taliban had regrouped into a serious military threat.
Candidate Obama promised to refocus America's resources on Afghanistan. But by the time President Obama sent 33,000 more troops to Afghanistan in December 2009, years of war in Iraq and Afghanistan had drained Western resources and sapped resolve to build a viable Afghan state.
And over time, his administration has grown weary of trying to tackle Afghanistan's seemingly intractable problems of poverty and corruption. The American people have grown weary too.
While most Americans are sympathetic to the plight of the Afghan people, they have become deeply skeptical of President Hamid Karzai's willingness to tackle corruption and political patronage and the coalition's chances of "budging a medieval society" into the modern world, says Ann Marlowe, a visiting fellow at the Hudson Institute, a policy research organization in Washington.
"With millions of veterans home and talking with their families and friends ... some knowledge of just how hard this is has percolated down," said Marlowe, who has traveled to Afghanistan many times.
It has also been hard to show progress on the battlefield.
World War II had its Normandy, Vietnam its Tet Offensive and Iraq its Battle of Fallujah. Afghanistan is a grinding slough in villages and remote valleys where success is measured in increments.
The Afghan war transformed into a series of small, often vicious and intense fights scattered across a country almost as large as Texas.
In July, 40 U.S. service members died in Afghanistan in the deadliest month for American troops so far this year. At least 31 have been killed this month ? seven when a helicopter crashed during a firefight with insurgents in what was one of the deadliest air disasters of the war. Ten others were gunned down in attacks from members of the Afghan security forces ? either disgruntled turncoats or Taliban infiltrators.
Many argue that bin Laden's death justifies a quick U.S. exit from Afghanistan. Others say it's important to stay longer to shore up the Afghan security forces and help build the government so that it can stand on its own. An unstable Afghanistan could again offer sanctuary to militants like al-Qaida who want to harm American and its allies, they say.
"Those of us who have been at this for a long time continue to think that it's important, and that we have a chance now of a path forward with a long-term perspective that will produce the results," said James Cunningham, the new U.S. ambassador to Afghanistan.
The U.S.-led coalition's combat mission will wind down in the next few years, leading up to the end of 2014 when most international troops will have left or moved into support roles.
Military analysts say the U.S. envisions a post-2014 force of perhaps 20,000 to hunt terrorists, train the Afghan forces and keep an eye on neighboring Iran and other regional powerhouse nations.
Americans aren't likely to know the number until later this year. But will anyone other than families of service personnel take note?
"I have heard others say that the danger that their spouses or children are serving in is just simply not being cared about," said Fred Wellman, a 22-year Army veteran who did three tours in Iraq. "I think a lot of veterans feel it is just forgotten."
Political satirist Garry Trudeau captured the apathy about the war in a comic strip this year showing a U.S. servicewoman stationed in Afghanistan calling her brother back home.
After he complains that his children have the flu and how he's struggling to keep up with their hectic hockey schedule, he asks her where she's calling from. She tells him she's in Afghanistan.
"Oh, right, right ..." her brother replies. "Wait, we're still there?"
___
Associated Press Writers Kristin Hall in Nashville, Tennessee and Jennifer Agiesta in Washington contributed to this report.
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Match Game Presents: The Many Hairstyles of ... - Tv Food and Drink
A few years back, I had the pleasure/honor/thrill of producing Phyllis Diller for GSN Live. The entire staff was all so excited about her impeding Friday appearance, we took great delight in the edit bay creating ?Phyllis teases? to air all week long. My personal favorite was this one, put together by our show?s editor, Sam West, in honor of Phyllis and her multitude of wigs, hats, falls, beads, and other head accessories. The woman could really pull off just about anything, don?t you think? You can see for yourself below. RIP Phyllis.
Tags: GSN Live Fred Roggin, GSN Live Heidi Bohay, GSN LIve Phyllis Diller, Phyllis Diller dead, Phyllis Diller game shows, Phyllis Diller GSN Game Show Network, Phyllis Diller Hairstyle, Phyllis Diller Match Game, Phyllis Diller on Match Game, Phyllis Diller television appearances
Posted in Game Shows and TV Retro 8 hours, 1 minute ago at 2:23 pm. Add a comment
Source: http://tvfoodanddrink.com/2012/08/match-game-presents-hairstyles-phyllis-diller/
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All India Pre Medical Test Biology Question Papers - PDF
All India Pre Medical Test Biology Question Papers
All India Pre Medical Test Biology Question Papers
Students who want to serve in Medical industry have to face different medical entrance
examinations like AIPMT. For the 15% merit positions of the Medical/ Dental Col eges of India
CBSE special y conduct this exam.
It stands for All India Pre Medical Test. It is directed by the Ministry of Health and Family
Welfare, India, CBSE only conducts exams, declares results and delivers Merit list to the
Directorate General of Health Services as per their directions.
In this exam 200 objective type questions have been asked from Physics, Chemistry and
Biology in a proportion of 25:25:50 in percentage. Students who clear this AIPMT exam have
to face the final exam which contains 120 objective type questions. Both exams are of 3 hr
duration.
The first is usually conducted on the 1st Sunday of April and the second is organized in May.
In both the AIPMT exams student's knowledge of the three subjects is tested. For each correct
question 4 marks added and for each incorrect 1 mark is deducted from total. Student needs
more than 50% marks to qualify for the main exam.
Know More About :- All India Pre Medical Test Physics Sample Paper
All India Pre-Medical Test is among the top entrance tests conducted in India. So for it
students need to practice very hard and for that they need AIPMT biology previous year
question paper along with the quality books that they can get from our portal.
This exam is conducted to take the admissions in the 15% merit seats of the top medical and
Dental col eges of India. It is organized in two levels.
Only those students who score more than 50% aggregate marks in their Prelims can get
selected for the Mains. Then for sure those students must have did a smart hard work using
AIPMT biology question papers and the sample Papers based on them after finishing their text
book and reference books studies. These sample papers are designed by our expert team
based on the AIPMT biology previous year question paper.
So when students practice these the indirectly they are preparing according to their syl abus.
Students it is necessary to practice these AIPMT biology question papers as they help you to
improve your Time management during exams, increases you confidence level, and increases
your accuracy level by increasing clarity of questions and the topic.
So students it is advised that practice with these AIPMT biology previous year question paper
as it is the only key to success. The syl abus covered in these sample papers, the reference
books whose information we are giving you and the AIPMT biology question papers is the
CBSE syl abus of the class 11th and 12th of the three subjects Biology, Physics and
Chemistry.
As these AIPMT biology previous year question paper is based on the complete syl abus so
your half of the topics gets covered practicing them as Biology is a Theoretical subject.
Students to know all about AIPMT biology previous year question paper just surf edurite and
avail whatever we have for you.
Read More About :- AIPMT Biology Sample Paper
ThankYou
Exams.Edurite.com
All India Pre Medical Test Biology Question Papers
Students who want to serve in Medical industry have to face different medical entrance
examinations like AIPMT. For the 15% merit positions of the Medical/ Dental Col eges of India
CBSE special y conduct this exam.
It stands for All India Pre Medical Test. It is directed by the Ministry of Health and Family
Welfare, India, CBSE only conducts exams, declares results and delivers Merit list to the
Directorate General of Health Services as per their directions.
In this exam 200 objective type questions have been asked from Physics, Chemistry and
Biology in a proportion of 25:25:50 in percentage. Students who clear this AIPMT exam have
to face the final exam which contains 120 objective type questions. Both exams are of 3 hr
duration.
The first is usually conducted on the 1st Sunday of April and the second is organized in May.
In both the AIPMT exams student's knowledge of the three subjects is tested. For each correct
question 4 marks added and for each incorrect 1 mark is deducted from total. Student needs
more than 50% marks to qualify for the main exam.
Know More About :- All India Pre Medical Test Physics Sample Paper
Exams.Edurite.com
Page : 1/3
All India Pre-Medical Test is among the top entrance tests conducted in India. So for it
students need to practice very hard and for that they need AIPMT biology previous year
question paper along with the quality books that they can get from our portal.
This exam is conducted to take the admissions in the 15% merit seats of the top medical and
Dental col eges of India. It is organized in two levels.
Only those students who score more than 50% aggregate marks in their Prelims can get
selected for the Mains. Then for sure those students must have did a smart hard work using
AIPMT biology question papers and the sample Papers based on them after finishing their text
book and reference books studies. These sample papers are designed by our expert team
based on the AIPMT biology previous year question paper.
So when students practice these the indirectly they are preparing according to their syl abus.
Students it is necessary to practice these AIPMT biology question papers as they help you to
improve your Time management during exams, increases you confidence level, and increases
your accuracy level by increasing clarity of questions and the topic.
So students it is advised that practice with these AIPMT biology previous year question paper
as it is the only key to success. The syl abus covered in these sample papers, the reference
books whose information we are giving you and the AIPMT biology question papers is the
CBSE syl abus of the class 11th and 12th of the three subjects Biology, Physics and
Chemistry.
As these AIPMT biology previous year question paper is based on the complete syl abus so
your half of the topics gets covered practicing them as Biology is a Theoretical subject.
Students to know all about AIPMT biology previous year question paper just surf edurite and
avail whatever we have for you.
Read More About :- AIPMT Biology Sample Paper
Exams.Edurite.com
Page : 2/3
ThankYou
Exams.Edurite.com
Source: http://pdfcast.org/pdf/all-india-pre-medical-test-biology-question-papers
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King Co Luxury Real Estate Up 10% ? Luxury Home Sales Shifting ...
Sales of luxury homes in the greater Seattle market have been rising for the past couple of years, and the most recent statistics confirm that the increases haven?t let up. ?Total luxury real estate sales in King County for 2012 thusfar have been up 9.8 percent as compared to the same point last year.
A total of 604 homes in King County have sold for over $1 million this year, including 91 homes over $2 million. ?The emergence of new jumbo credit options has certainly helped out the luxury buying crowd, but confidence in the local job market has also had a strong hand in turning high-end buyers from fence-sitters to big bidders.
An interesting side note in this upswing is the shift in luxury sales from Seattle proper to the Eastside. ?While King County luxury home sales are up, luxury sales within the city of Seattle are actually down 5.9 percent for the year. ?That number can be taken with a grain of salt, since overall Seattle sales are up around 15% for the year, but the luxury market was outpaced significantly just across Lake Washington.
Sales of luxury homes on the Eastside are up 23.9 percent so far this year (including?Bellevue, Kirkland, Redmond, Mercer Island, Medina, Issaquah, Sammamish, the Points and Clyde Hill). ?There were 386 home sales of over $1 million so far this year on the Eastside, including 63 sales over $2 million (also an 8.6 percent increase). ? Clearly the confidence of luxury real estate buyers on the Eastside has returned in force, while the overall market in Seattle?s strength has not quite reignited the local luxury home buyers.
Significant Eastside Luxury Home Sales in 2012:
3645 Hunts Point Rd, Hunts Point WA 98004
$11,000,000
Undisclosed Address, Yarrow Point WA 98004
$8,250,000
Top Seattle Luxury Real Estate Sale, 2012:
Undisclosed Address, Denny Blaine Neighborhood, Seattle WA 98122
??Seattle Homes, LLC: ? Sam DeBord, Managing Broker, Realtor
Coldwell Banker Seattle: Coldwell Banker Danforth & Associates
Twitter |?Facebook |?LinkedIn | Google + | Sam (at) SeattleHome.com
Data Source: NWMLS ? The Northwest Multiple Listing Service did not compile or publish this information.
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Remodel Kitchen Cost | The Best Cabinets
Do you think you?re a property owner who?s going to be seeking to have region renovated? If you?re, you possible already know just that you simply, pretty much, come with an limitless number of choices.
Together with what you look for remodeled and in what way you wish every thing to take a look, also you can choose the way renovating may get accomplished. Though quite a few home owners decide to perform their own personal kitchen?s upgrading, you?ll find other people who choose to use assistance from an expert. That professional is often typically called a professional. Among the finest tips on how to decide if you don?t you can utilize an established contractor would be to study the pros and cons of doing this.
Since you may have deemed, you can find a large quantity of benefits to your cooking area re-designed by way of skilled. Perhaps, the most advantage of a professional home remodeling occupation is the actual result. In almost all cases, so as to a reliable remodeling employment is superior to engineered to be performed by someone with out encounter. While it may sound straightforward to swap the lighting in your kitchen perhaps kitchen countertops, so as to it?s not at all often as easy as it appears. In lieu of taking the time to learn, quite a few property owner immediately choose a reliable specialist.
While we?re talking about time, you?ll also find this time is an additional benifit of employing a specialized contractor to rework region. Considering the fact that expert technicians are knowledgeable at what they do, they won?t only deliver top quality operate, but they also will likely create it in a relativity small amount of time. Since the ordinary owner of a house is brand new to the ins and outs of redesigning, normally, many times, it can take them more time to perform any redesigning assignments. Even if this would possibly not always be described as a problem, it could be should you be tight on time or for anyone who is with a contract. If you are, you might be able to profit hugely from using the services of an established service provider.
Safety is another benefit to working with an expert service provider to obtain region re-designed. Regardless of whether you are looking at home improvement your entire home or simply just centering on a selected portion of it, such as your cabinets, you will see that it is quite damaging to transform your own your kitchen, in particular unless you know what you?re doing. Depending on the specific remodeling challenge in question, you may have to use pointed equipment, for example container blades and saws. A single tiny move and instead of dealing with your your kitchen, you will be investing all of your morning in the er. When specialist installers make mistakes that may result in injury, all those injuries rarely appear.
Even though it might appear as if you can just really benefit from by using a skilled builder to transform your kitchen area, in addition there are cons to selecting help of one particular. One of those particular cons would be the expense. Due to the fact specialized contractors are perfect at their work, sometimes they ask for because of it. How much money is that you will be charged will all be determined by which kind of renovating you want executed as well as the person or organization that you are wanting to assist. Thankfully that you simply could possibly create a payment plan or policy for loans, as long as you have a very beneficial credit rating.
Yet another disadvantage in having a specialist redesign your kitchen for you personally seemed to be mentioned previously just as one advantage. That?s the result. Sad to say, is simple difficult to figure out whether anyone or firm that statements to be expert is actually. Prior to saying yes to use a specific contractor, often a person or perhaps a corporation, you are advised to ask for photographs in their earlier operate and you will should also speak to recent customers. This will aid to ensure that your professional home renovating project spins view that it should be, specialist.
As you can see, there are many of pluses and minuses to presenting a professional professional to transform the kitchen. Maybe, the obvious way to determine what you should do is maintain these points at heart after which look at your wants. In case a expert service provider typically offer you what you are looking for then it is usually best if you utilize one.
Source: http://artisancabinetryinc.com/2012/08/remodel-kitchen-cost-2/
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Wednesday, August 15, 2012
New ad campaign portrays caregivers' call for help
WASHINGTON (AP) ? A woman grips her car's steering wheel and silently lets out a scream as her frail father, on oxygen, coughs beside her and her kids play around in the back seat.
The frustration portrayed in an arresting new public service announcement is recognizable to millions of Americans who struggle to care for aging loved ones while holding down jobs, raising children and taking care of their own health.
"I take care of her, but who takes care of me?" says another one of the public service announcements from the nonprofit Ad Council, which is distributing the ads for TV, radio, print and online use. It's part of a major campaign from AARP and the Ad Council beginning Thursday to raise awareness of the impact of family caregiving as the nation rapidly grays ? and to point overwhelmed families toward resources that may ease the strain.
"Most caregivers don't know where to turn for help," said AARP vice president Debra Whitman, whose own family has experienced caregiving twice, for her grandmother and her mother-in-law.
Even knowing what to ask can be a hurdle. That's what Andrea Phillips of Alexandria, Va., discovered when her mother, now 74, visited from Chicago a few years ago and got too sick to go home. She recovered from a heart problem only to be diagnosed with early Alzheimer's.
Phillips, a lawyer with 1- and 4-year-old daughters, raced to find nearby senior housing that her mother would accept and could afford. But already she's having to cobble together additional care as the Alzheimer's worsens. She says her mother skips her prepaid meals in favor of a cookie stash, misses medication despite Phillips' daily take-your-pills phone calls and is embarrassed to find herself struggling to remember and perform personal hygiene ? the kind of day-to-day issues that health providers didn't address.
"I do constantly feel that I'm playing catch-up," said Phillips, adding that she feels guilty when she gets frustrated. "I'm trying to find the right resources so Mom and I can continue to have a good relationship."
Although they often don't identify themselves as "caregivers," more than 42 million Americans perform some form of consistent care for older or impaired adult relatives or friends, according to a 2009 estimate. It can range from paying bills, to driving Mom to doctor appointments, to more hands-on care such as bathing, and even tasks once left to nurses such as the care of open wounds.
"At first you're just helping out Mom. Then it can become more than a fulltime job," said AARP's Whitman.
She described the average U.S. caregiver as a 49-year-old woman who on top of her regular job provides nearly 20 hours a week of unpaid care to her mother for nearly five years.
An AARP report found family members provide a staggering $450 billion worth of unpaid care annually ? and other research makes clear that the stress and the time involved can take a toll on the caregivers' own health and finances as they put off their own doctor visits, dip into their savings and cut back their working hours.
Adding to the challenge is that more and more people are living well into their 90s, as Census figures show the oldest-old are the fastest growing segment of the population.
Consider Oona Schmid's father, who is 96 and has advanced dementia. The Arlington, Va., woman has overseen his care for a decade, since her mother died ? and said she could have better planned how to pay for it if only someone had warned her how long people can live with dementia. She said the bill at her father's assisted-living facility has reached nearly $8,000 a month as he now needs round-the-clock care.
"I don't think he knows who I am, but he still smiles when he sees me," Schmid said. She choked up as she described the pull she feels between her responsibilities to her father and to her 3-year-old son, fretting that there's no money left to set aside for her son's education.
Schmid, 41, works fulltime, pet-sits for extra cash and is exploring options to save on her father's care.
"Maybe this is a terrible thing to say but I'm terrified of how long he's going to live and how much it's going to cost," she said.
Like Schmid's father, very few Americans have purchased private, and pricey, long-term care insurance, and Medicare doesn't pay for that kind of care. That's why family members wind up performing so much of it for so long. The Obama administration last fall ended efforts to establish a government-sponsored program to make long-term care insurance more affordable, finding it financially unsustainable.
A key message of the new campaign is for caregivers not to neglect their own needs.
The ads direct people to AARP's website ? www.aarp.org/caregiving ? to find information and services from that organization and others, what Whitman describes as a one-stop starting point for resources.
The site offers Web chats with caregiving experts, online support groups, legal documents and links to such programs as locators for care providers ? www.eldercare.gov ? or respite services ? www.archrespite.org. A new "Prepare to Care" brochure offers to-do checklists for families new to caregiving, and people not as web-savvy can call a hotline at 877-333-5885.
Too many caregivers don't know such services exist, or even that they can ask their loved ones' doctors to refer them for help until there's a crisis, said Dr. Eileen Callahan, a geriatrician at New York's Mount Sinai Medical Center who isn't involved with the AARP campaign.
The AARP project is broader than another new effort targeting caregivers ? a government website that, as part of the National Alzheimer's Plan, offers families information specific to dementia care at www.alzheimers.gov.
Mount Sinai's Callahan said national efforts to educate all caregivers, regardless of the health problem, are long overdue.
"They should not feel so isolated," she said. "It is so incredibly sad."
The latest story in the joint AP-APME project looking at the aging of the baby boomers and the impact of this so-called silver tsunami on society.
Source: http://news.yahoo.com/ad-campaign-portrays-caregivers-call-help-185651266.html
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Study links recession to 1,000 suicides
LONDON (Reuters) - A painful British economic recession and rising unemployment may have driven more than 1,000 people in England to commit suicide, according to a scientific study published on Wednesday.
The study, a so-called time-trend analysis which compared the actual number of suicides with those expected if pre-recession trends had continued, reflects findings elsewhere in Europe where suicides are also on the rise.
"This is a grim reminder after the euphoria of the Olympics of the challenges we face and those that lie ahead," said David Stuckler, a sociologist at Cambridge University who co-led the study, published in the British Medical Journal (BMJ).
The analysis found that between 2008 and 2010 there were 846 more suicides among men in England than would have been expected if previous trends continued, and 155 more among women.
Between 2000 and 2010 each annual 10 percent increase in the number of unemployed people was associated with a 1.4 percent increase in the number of male suicides, the study found.
The analysis used data from the National Clinical and Health Outcomes Database and the Office of National Statistics.
Keith Hawton, a professor at the Centre for Suicide Research at Oxford University who was not involved in the study, said its findings were "of considerable interest and certainly raise concerns", but that they must be interpreted carefully.
"It is also important that they are not over-dramatised in a way that might increase thoughts of suicide in those affected by the recession," he said in an emailed comment.
Stuckler, who worked with researchers from Liverpool University and the London School of Hygiene and Tropical Medicine, stressed while this kind of statistical study could not establish a causal link, the power of the associations was strong. Its conclusions were strengthened by other indicators of rising mental health problems, stress and anxiety, he added.
He also pointed out the study showed a small reduction in the number of suicides in 2010 which coincided with a slight recovery in male employment.
DEPRESSION, ANXIETY, ALCOHOL ABUSE
A survey of 300 family doctors published by the Insight Research Group on Tuesday found that 76 percent of those questioned about the effects of the economic crisis said they thought it was making people unhealthier, leading to more anxiety, abortions and alcohol abuse.
Data this month from the government's Health and Social Care Information Centre showed the number of prescriptions dispensed in England for antidepressants rose 9.1 percent in 2010.
A study published last July, also by Stuckler, found that across Europe, suicide rates rose sharply from 2007 to 2009 as the financial crisis drove unemployment up and squeezed incomes.
The countries worst hit by severe economic downturns, such as Greece and Ireland, saw the most dramatic increases in suicides.
In Britain, there's little doubt times have been getting harder. The economy has shrunk for the last nine months and now produces 4.5 percent less than before the economic crisis.
Many Britons have had the worst squeeze in living standards for 40 years and the crisis has hit young people hard, with youth unemployment soaring above 20 percent.
Stuckler's BMJ study found that the number of unemployed men rose on average across Britain by 25.6 percent each year from 2008 to 2010, a rise associated with a yearly increase in male suicides of 3.6 percent.
"Much of men's identity and sense of purpose is tied up with having a job. It brings income, status, importance..." Stuckler said in a telephone interview.
"And there's also a pattern in the UK where men are three times more likely to commit suicide than women, while women are much more likely to report being depressed and seek help."
Hawton noted that increases in suicides at times of economic recession had been reported before - for example in the Great Depression of the 1930s and in the economic downturn in South-east Asia during the 1990s.
The World Health Organisation estimates that every year, almost a million people commit suicide - a rate of 16 per 100,000, or one every 40 seconds. It also estimates that for every suicide, there are up to 20 attempted ones.
(Corrects first paragraph to remove reference to austerity policies, which began after the period of the study)
(Editing by Pravin Char)
Source: http://news.yahoo.com/study-links-recession-1-000-suicides-084957445.html
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Former UFC fighter Jason ?Mayhem? Miller arrested, caught naked in church
Former UFC and Strikeforce fighter Jason "Mayhem" Miller was arrested Monday in Mission Viejo , Calif., after allegedly breaking into a church and vandalizing it with a fire extinguisher.? Police responding to the call reportedly found Miller sitting on a couch, naked but coherent.? He was taken into custody and charged with suspicion of burglary, and is undergoing a mental evaluation.
Miller found limited success in his time in the Octagon but was considered one of the sport's most colorful personalities.? He was also the host of MTV's popular reality show "Bully Beatdown."? Miller publicly retired from competition in May of this year after a lackluster performance at UFC 146 led to him to being fired.? Since then, he's tried his hand at stand-up comedy, and last week he engaged in an argument with UFC president Dana White over Twitter, where he said "Kill yourself @danawhite we are all begging you."
Follow Jim Genia on Twitter here.
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Tuesday, August 14, 2012
Parks And Recreation Olympics Promos (Video) | SportsGrid
Media MonsterVideo
Yeah, the Olympics were almost over when NBC posted this video on Friday of Parks and Recreation characters Ron Swanson and Tom Haverford wrestling (for the record, there were Olympics-themed promos like this for a few different shows), but does it even matter? It?s Ron Swanson owning an exceptionally weak man ? i.e. internet porn.
Really, Ron Swanson is such guaranteed internet gold (why do you think New Era tapped Nick Offerman to co-star in its series of web-based rivalry ads during baseball season?) that the only thing a bit surprising to us is the relatively modest view count ? as of this writing, at least ? of the video above. Sure, Parks and Rec isn?t a mega-hit (or even a hit, at least among general audiences), but we?d have thought viral traffic would win the day. Maybe everyone was busy burying NBC for its coverage of the actual Olympics to notice.
Oh, and that wasn?t the only Parks and Rec Olympics promo, either. There was also this, and even another Swanson-centric one:
Wait ? Ron eating disgusting quantities of food in front of a rapt audience while spouting in-your-face nationalism, and even that hasn?t broken the internet? We all need to step our games up.
[Gunaxin]
Source: http://www.sportsgrid.com/media/parks-and-recreation-olympics-promos/
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Nano, photonic research gets boost from new 3-D visualization technology
![[ Back to EurekAlert! ]](http://www.eurekalert.org/images/back2e.gif){kind=small}
Public release date: 13-Aug-2012[ | E-mail |
Share ] Contact: Tona Kunz
tkunz@anl.gov
630-252-5560
DOE/Argonne National Laboratory
ARGONNE, Ill. (August 12, 2012) -- For the first time X-ray scientists have combined high-resolution imaging with 3-D viewing of the surface layer of material using X-ray vision in a way that does not damage the sample.
This new technique expands the range of X-ray research possible for biology and many aspects of nanotechnology, particularly nanofilms, photonics, and micro- and nano-electronics. This new technique also reduces "guesswork" by eliminating the need for modeling-dependent structural simulation often used in X-ray analysis.
Scientists from the Advanced Photon Source and Center for Nanoscale Materials at the U.S. Department of Energy's (DOE) Argonne National Laboratory have blended the advantages of 3-D surface viewing from grazing-incident geometry scattering with the high-resolution capabilities of lensless X-ray coherent diffraction imaging (CDI). The new technique, an adaptation of existing detector technology, is expected to work at all X-ray light sources.
"This is the future of how we will visualize structure of surfaces and interface structures in materials science with X-rays," said Argonne scientist Jin Wang, the lead author of "Three-Dimensional Coherent X-ray Surface Scattering Imaging near Total External Reflection" published on-line August 12, 2012, in the journal Nature Photonics.
By adjusting the angle with which the X-rays scatter off the sample, Wang and fellow Argonne scientists brought the 3-D power of the new imaging technique to the surface layers of the sample. In nanotechnology, most of the atomic interactions that control the functionality and efficiency of a product, such as a semiconductor or self-assembled nanostructure, occur at or just below the surface. Without a direct 3-D viewing capability, scientists have to rely on models rather than direct measurement to estimate a surface structure's thickness and form, which weakens confidence in the estimate's accuracy.
Using grazing-incidence geometry, rather than traditional CDI transmission geometry, scientists eliminated the need for modeling by using the scattering pattern to directly reconstruct the image in three dimensions.
Conventional X-ray imaging techniques allow for 3-D structural rendering, but they have lower image resolution and, therefore, greater uncertainty. Plus, in some cases, the X-rays' intensity destroys the sample. This new APS-designed technique potentially can image a sample with a single X-ray shot, making it non-destructive, a desirable quality for research on biological cells and features formed by organic materials.
Another benefit is the ability to expand CDI viewing from the nanometer to the millimeter scale when the X-ray beamline impinges on the sample at a glancing angle. This innovation allows scientists to relate the behavior of a bundle of atoms or molecules to that of an entire device. This areathe mesoscale, between nanoresearch and applied technologyhas been a particularly difficult area for scientists to access. In nanotechnology, this area is thought to hold promise for making stronger, more flexible and more efficient materials. In biology, it connects intercellular behavior with the activity of individual cells and the larger organism.
"Hopefully this technique will be applied to research in biology, microelectronics and photonics" said Tao Sun, a postdoctoral research fellow working at the APS and the first author on the research. "This technique holds great promise because the resolution we can reach is only limited by wavelength, a fraction of a nanometer. So the APS upgrade and other advances in light source and detector technology will easily provide even higher-resolution images than we have achieved in this work."
###
The Advanced Photon Source at Argonne National Laboratory is one of five national synchrotron radiation light sources supported by the U.S. Department of Energy's Office of Science to carry out applied and basic research to understand, predict, and ultimately control matter and energy at the electronic, atomic, and molecular levels, provide the foundations for new energy technologies, and support DOE missions in energy, environment, and national security. To learn more about the Office of Science X-ray user facilities, visit http://science.energy.gov/user-facilities/basic-energy-sciences/.
Argonne National Laboratory seeks solutions to pressing national problems in science and technology. The nation's first national laboratory, Argonne conducts leading-edge basic and applied scientific research in virtually every scientific discipline. Argonne researchers work closely with researchers from hundreds of companies, universities, and federal, state and municipal agencies to help them solve their specific problems, advance America's scientific leadership and prepare the nation for a better future. With employees from more than 60 nations, Argonne is managed by UChicago Argonne, LLC for the U.S. Department of Energy's Office of Science.
DOE's Office of Science is the single largest supporter of basic research in the physical sciences in the United States, and is working to address some of the most pressing challenges of our time. For more information, please visit science.energy.gov.
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AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
Public release date: 13-Aug-2012[ | E-mail |
Share ] Contact: Tona Kunz
tkunz@anl.gov
630-252-5560
DOE/Argonne National Laboratory
ARGONNE, Ill. (August 12, 2012) -- For the first time X-ray scientists have combined high-resolution imaging with 3-D viewing of the surface layer of material using X-ray vision in a way that does not damage the sample.
This new technique expands the range of X-ray research possible for biology and many aspects of nanotechnology, particularly nanofilms, photonics, and micro- and nano-electronics. This new technique also reduces "guesswork" by eliminating the need for modeling-dependent structural simulation often used in X-ray analysis.
Scientists from the Advanced Photon Source and Center for Nanoscale Materials at the U.S. Department of Energy's (DOE) Argonne National Laboratory have blended the advantages of 3-D surface viewing from grazing-incident geometry scattering with the high-resolution capabilities of lensless X-ray coherent diffraction imaging (CDI). The new technique, an adaptation of existing detector technology, is expected to work at all X-ray light sources.
"This is the future of how we will visualize structure of surfaces and interface structures in materials science with X-rays," said Argonne scientist Jin Wang, the lead author of "Three-Dimensional Coherent X-ray Surface Scattering Imaging near Total External Reflection" published on-line August 12, 2012, in the journal Nature Photonics.
By adjusting the angle with which the X-rays scatter off the sample, Wang and fellow Argonne scientists brought the 3-D power of the new imaging technique to the surface layers of the sample. In nanotechnology, most of the atomic interactions that control the functionality and efficiency of a product, such as a semiconductor or self-assembled nanostructure, occur at or just below the surface. Without a direct 3-D viewing capability, scientists have to rely on models rather than direct measurement to estimate a surface structure's thickness and form, which weakens confidence in the estimate's accuracy.
Using grazing-incidence geometry, rather than traditional CDI transmission geometry, scientists eliminated the need for modeling by using the scattering pattern to directly reconstruct the image in three dimensions.
Conventional X-ray imaging techniques allow for 3-D structural rendering, but they have lower image resolution and, therefore, greater uncertainty. Plus, in some cases, the X-rays' intensity destroys the sample. This new APS-designed technique potentially can image a sample with a single X-ray shot, making it non-destructive, a desirable quality for research on biological cells and features formed by organic materials.
Another benefit is the ability to expand CDI viewing from the nanometer to the millimeter scale when the X-ray beamline impinges on the sample at a glancing angle. This innovation allows scientists to relate the behavior of a bundle of atoms or molecules to that of an entire device. This areathe mesoscale, between nanoresearch and applied technologyhas been a particularly difficult area for scientists to access. In nanotechnology, this area is thought to hold promise for making stronger, more flexible and more efficient materials. In biology, it connects intercellular behavior with the activity of individual cells and the larger organism.
"Hopefully this technique will be applied to research in biology, microelectronics and photonics" said Tao Sun, a postdoctoral research fellow working at the APS and the first author on the research. "This technique holds great promise because the resolution we can reach is only limited by wavelength, a fraction of a nanometer. So the APS upgrade and other advances in light source and detector technology will easily provide even higher-resolution images than we have achieved in this work."
###
The Advanced Photon Source at Argonne National Laboratory is one of five national synchrotron radiation light sources supported by the U.S. Department of Energy's Office of Science to carry out applied and basic research to understand, predict, and ultimately control matter and energy at the electronic, atomic, and molecular levels, provide the foundations for new energy technologies, and support DOE missions in energy, environment, and national security. To learn more about the Office of Science X-ray user facilities, visit http://science.energy.gov/user-facilities/basic-energy-sciences/.
Argonne National Laboratory seeks solutions to pressing national problems in science and technology. The nation's first national laboratory, Argonne conducts leading-edge basic and applied scientific research in virtually every scientific discipline. Argonne researchers work closely with researchers from hundreds of companies, universities, and federal, state and municipal agencies to help them solve their specific problems, advance America's scientific leadership and prepare the nation for a better future. With employees from more than 60 nations, Argonne is managed by UChicago Argonne, LLC for the U.S. Department of Energy's Office of Science.
DOE's Office of Science is the single largest supporter of basic research in the physical sciences in the United States, and is working to address some of the most pressing challenges of our time. For more information, please visit science.energy.gov.
[ | E-mail | Share ] ?
AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
Source: http://www.eurekalert.org/pub_releases/2012-08/dnl-npr081312.php
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Arts & Entertainment: How Kosmoratik Is Changing The Music ...
By Freida Lamb
One notable band that is quickly gaining notoriety in the city of Oslo, Norway is the band Kosmoratik. This band is quickly becoming very popular due to their creative style and interesting use of a wide range of instruments. If you are searching for a band that offers a mellow yet highly original sound for you to enjoy, you will likely love the range of music being created by this band.
Progressive pop is the foundation upon which this band?s recordings are made. Progressive pop is the result of an earlier revolution in the music industry known as progressive rock. kosmoratik?s love of progressive rock and progressive pop has helped them develop numerous innovative recordings that maintain a very unique style now known as symphonic pop.
Symphonic pop is a highly original form of music. It utilizes new sounds and unusual combinations of instruments. These sounds and instrument combinations gives it an essence that is unlike any other form of music.
Symphonic pop is the antithesis to this approach to producing music. The style of music Kosmoratik uses is built upon the innovative and revolutionary sense of style progressive rock bands developed. They do so in defiance of the continuing trend of rehashing the same sounds for profits many bands follow.
In the 1960?s and 70?s, artists interested in spreading a revolution of innovative music developed creative sounds and creative uses for instruments to push the boundaries of their craft. Bands that chose to push the limits around this time were able to create compositions that were completely original. This form of music became very popular when it was first released and it still is very popular even today.
The music created by kosmoratik is available for free on many websites today. Fans can also contact the band directly through their social media portals. Due to the remarkably original and innovative recordings this band has released in the past, fans interested in new soothing and mellow symphonic pop styled recordings are highly anticipating the next album release of this band. Their upcoming album releases will surely stretch the boundaries of traditional pop music through the use of newly combined sounds accompanied by pleasing vocals and interesting instrument selections.
Source: http://arts-an-entertainment.blogspot.com/2012/08/how-kosmoratik-is-changing-music.html
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Pfizer buys rights to OTC heartburn drug Nexium
TRENTON, N.J. (AP) ? Drugmakers AstraZeneca PLC and Pfizer Inc. have reached a deal giving Pfizer future rights to sell a nonprescription version of AstraZeneca's blockbuster heartburn drug, Nexium, as early as 2014.
The deal, announced late Monday, could help Pfizer expand its consumer health business as it continues a restructuring meant to strengthen its core drug business and divest its infant-formula and animal-health businesses. It would also help AstraZeneca to still get some revenue from one of its top sellers after generic competition hits. And the companies said they're exploring the idea of a partnership to convert other AstraZeneca prescription drugs to over-the-counter medicines.
In order to sell nonprescription Nexium, New York-based Pfizer must first win approval from the Food and Drug Administration and regulators in other countries. The drug, which treats ulcers and acid-reflux disease by reducing excess stomach acid, is known chemically as esomeprazole.
Nexium was the world's fifth-best-selling medicine last year, with global revenue of nearly $8 billion, according to health data firm IMS Health. The drug has long been touted in TV commercials as "the purple pill" that stops heartburn for 24 hours.
Viagra maker Pfizer said it is aiming to apply to the FDA in the first half of 2013 for approval of nonprescription Nexium in 20-milligram, delayed-release capsules. An application to sell the same dosage, but in tablet form, was filed with the European Medicines Agency in June.
If it wins approval, Pfizer aims to launch over-the-counter Nexium in the U.S. in 2014. The drug's patent is slated to expire in the U.S. that spring. Pfizer plans to begin selling the product in other countries after that.
Pfizer will pay London-based AstraZeneca $250 million upfront, then royalty and other payments based on product launches in various countries and sales revenue.
Both companies adjusted their 2012 financial forecasts as a result of the deal.
Pfizer lowered its earnings-per-share forecast by 2 cents, to $1.21 to $1.36 per share, or a range of $2.12 to $2.22 excluding one-time items. AstraZeneca said it will recognize the $250 million upfront payment as "other income" this year. That will increase its earnings per share by about 16 cents, to a range of $6 to $6.30.
Shares in Pfizer were up 3 cents to $23.75 in extended trading following the announcement. U.S.-traded shares of AstraZenica rose 38 cents to $47.49.
AstraZeneca, best known for cholesterol drug Crestor, launched Nexium in the U.S. in 2001 and in Europe in 2000. It will still manufacture and sell prescription Nexium, and will supply Pfizer with the nonprescription version once that's approved.
AstraZeneca and a predecessor company have had a marketing partnership involving prescription Nexium and an older, similar heartburn drug called Prilosec, with Merck & Co. of Whitehouse Station, N.J., since 1982. Merck holds an interest in the two drugs and receives quarterly payments from AstraZeneca that total roughly $1 billion per year. That arrangement is unaffected by the new deal with Pfizer, although Merck and AstraZeneca amended their arrangement in June to give AstraZeneca an option to buy out Merck's interest in 2014.
Pfizer once had a large consumer-health products business, but sold its portfolio, including Listerine, to Johnson & Johnson several years ago. Pfizer now has several well-known consumer health products, including ChapStick, Centrum vitamins and the Dr. Scholl's foot care and Coppertone sun care product lines. Those were all acquired when Pfizer bought Schering-Plough Corp. in November 2009.
Pfizer and AstraZeneca said Monday they have signed a deal giving Pfizer first refusal on the nonprescription rights to AstraZeneca's Rhinocort Aqua. That's a nasal pump spray for treating hay fever and dust mite allergies.
___
Linda A. Johnson can be followed at http://twitter.com/LindaJ_onPharma.
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Clinton, Minnelli among stars at Hamlisch funeral
FILE - This undated file image originally provided by Columbia Artists Management Inc. LLC shows Marvin Hamlisch. Friends and admirers of Marvin Hamlisch will gather Tuesday morning to bid farewell to the celebrated songwriter who was hailed as "the people's composer." Hamlisch's funeral is to be held at Congregation Emanu-El, a prominent Upper East Side synagogue. The composer died Aug. 6 in Los Angeles at age 68. (AP Photo/Columbia Artists Management Inc. LLC, Jason Cohn)
FILE - This undated file image originally provided by Columbia Artists Management Inc. LLC shows Marvin Hamlisch. Friends and admirers of Marvin Hamlisch will gather Tuesday morning to bid farewell to the celebrated songwriter who was hailed as "the people's composer." Hamlisch's funeral is to be held at Congregation Emanu-El, a prominent Upper East Side synagogue. The composer died Aug. 6 in Los Angeles at age 68. (AP Photo/Columbia Artists Management Inc. LLC, Jason Cohn)
NEW YORK (AP) ? Friends and admirers of Marvin Hamlisch including Bill Clinton and Ann-Margret gathered Tuesday in New York City to bid farewell to the celebrated songwriter hailed as "the people's composer."
Clinton called Hamlisch, whose casket was covered in yellow flowers, a "great, giving genius." Howard Stringer, head of Sony, called him "the merriest of minstrels."
Hamlisch died Aug. 6 in Los Angeles at age 68.
Other guests included Liza Minnelli, ex-Yankee manager Joe Torre, Idina Menzel, Kelli O'Hara, Raul Esparza, Leslie Uggams, Richard Gere and Tony Danza.
Hamlisch composed or arranged hundreds of scores for musicals and movies, including "A Chorus Line" on Broadway and the films "The Sting," ''Sophie's Choice," ''Ordinary People" and "The Way We Were."
His funeral was held at Congregation Emanu-El, a prominent synagogue where George Gershwin's funeral was held in 1937.
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Differences in the genomes of related plant pathogens
Monday, August 13, 2012
Many crop plants worldwide are attacked by a group of fungi that numbers more than 680 different species. After initial invasion, they first grow stealthily inside living plant cells, but then switch to a highly destructive life-style, feeding on dead cells. While some species switch completely to host destruction, others maintain stealthy and destructive modes simultaneously. A team of scientists led by Richard O'Connell from the Max Planck Institute for Plant Breeding Research in Cologne and Lisa Vaillancourt from University of Kentucky in Lexington have investigated the genetic basis for these two strategies. The researchers found that pathogen life-style has moulded the composition of these fungal genomes and determines when particular genes are switched on. They also discovered surprising new functions for fungal infection organs.
Colletotrichum fungi cause rots and leaf spot diseases which are spread by wind and rain splash. They cause devastating economic losses on food and biofuel crops running into billions of euros each year. While some species attack many different plants, others are highly selective and attack just one host plant. The two species investigated by O'Connell and his colleagues differ in their life-style and their host specificity. One species preferentially attacks crucifers, including thale cress (Arabidopsis thaliana), a model plant important for biologists. Within just a few hours, this pathogen switches its metabolism towards the complete destruction of the plant cells. For this fungus, benign coexistence and massive destruction are separated in time. The other species studied is specifically adapted to maize. In one part of the plant it produces proteins to promote symptomless coexistence, while elsewhere it produces proteins to break-down and digest plant cells. In this case, the two life-styles are spatially separated.
The strength of this work, published in Nature Genetics, is that the researchers analysed both the genome and transcriptome of these two fungi. "The transcriptome reveals which genes are switched on and when. Several other fungal genomes have already been decoded, but never with such detailed information about if and when each gene is used during plant infection", says O'Connell. For example, both genomes have similar numbers of genes for hemicellulase enzymes, with which the plant cell wall is decomposed. However, the maize fungus switches on many more of these genes because the cell walls of maize contain more hemicellulose than do plants attacked by the Arabidopsis fungus. "This difference could not have been identified simply from cataloguing the numbers of such genes in the genome: transcriptome data are essential to obtain this information", explains O'Connell.
The genomes of the two pathogens are similar in size, but the Arabidopsis fungus accommodates more genes in its genome, probably as a result of its broader host range. A pathogen that attacks a single plant requires fewer genes than one which colonizes many different plants. This is especially true for "effector" genes, which are required by the fungus to protect itself from the plant's defence responses. Both fungi have remarkably large numbers of genes for producing secondary metabolites, which are small molecules with potential roles during infection. "We are not aware of any other phytopathogenic fungi that produce so many secondary metabolites", says Jochen Kleemann who, together with other colleagues from the Max Planck Institute for Plant Breeding Research in Cologne, was also involved the study. "The genes for these products are switched on very early on during infection and are therefore potential targets for plant protection. But first we need to understand more about the functions of these molecules", continues Kleemann.
The scientists also discovered previously unknown functions of the fungal adhesion organ, the appressorium. The appressorium is formed after a fungal spore lands on the leaf surface and builds up a high pressure, with which the fungus pushes itself into the interior of the plant cell, like a finger into an inflated balloon. "On a leaf, the adhesion organ switches on completely different genes than when it is located on a plastic surface. It must in some way recognize where it is", says O'Connell. The adhesion organ would thus appear not only to open the door into the plant cell, but also to sense the presence of the plant. "Appressoria were discovered almost 130 years ago, but it is only from our research that it has become clear that they also have a sensing function", says Kleemann.
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Richard J O'Connell et al.
Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses
Nature Genetics, August 12, 2012, DOI: 10.1038/ng.2372
Max-Planck-Gesellschaft: http://www.mpg.de
Thanks to Max-Planck-Gesellschaft for this article.
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Source: http://www.labspaces.net/122504/Differences_in_the_genomes_of_related_plant_pathogens_
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