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Monday, June 17, 2013
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Source: http://www.houserepairtalk.com/f17/crack-above-window-new-construction-16124/
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Riot police disperse protesters in Istanbul park
ISTANBUL (AP) ? Riot police fired water cannons and tear gas as they drove protesters out of Istanbul's Taksim Square and neighboring Gezi Park on Saturday, an intervention that came shortly after the prime minister warned that security forces "know how to clear" the area, which had become a symbol of the biggest anti-government protests in decades.
Within a half-hour, the sweep by white-helmeted riot police had emptied the park, leaving a series of colorful, abandoned tents behind. Bulldozers moved in afterward, scooping up debris as crews of workmen in hard hats and fluorescent yellow vests tore down the tents. Protesters put up little physical resistance, even as plain-clothes police shoved many of them to drive them from the park.
White smoke billowed skyward as a phalanx of riot police marched inside the park on Saturday. They tore down protesters' banners, toppled a communal food stall, and sprayed tear gas over the tents and urging those inside to get out.
Images on Turkish TV showed activists carrying one woman on a stretcher through a rank of riot police and into an ambulance, and a man splayed out, motionless, on the ground before a few others picked him up barehanded and hauled him away. For over two weeks, protesters had defied Prime Minister Recep Tayyip Erdogan's warnings to vacate the area.
Tayfun Kahraman, a member of Taksim Solidarity, an umbrella group of protest movements, said an untold number of people in the park had been injured ? some from rubber bullets.
"Let them keep the park, we don't care anymore. Let it all be theirs. This crackdown has to stop. The people are in a terrible state," he told The Associated Press by phone.
A brutal police intervention on May 31 against those protesting plans to redevelop the square and the park had sparked the biggest anti-government protests in Turkey in decades and dented Erdogan's international reputation.
The protests, which at one point spread to dozens of Turkish cities and towns, turned into a much broader expression of discontent about Erdogan's government, and what many say is his increasingly authoritarian decision-making.
Erdogan, who was elected with 50 percent of the vote for his third term in 2011, vehemently rejects the accusations by protesters and points to his strong support base
As they entered the park on Saturday police shouted to the protesters: "This is an illegal act, this is our last warning to you ? Evacuate."
Shortly before the police launched their operation, Erdogan had threatened protesters in a boisterous speech in Sincan, a suburb of the capital Ankara, that is a stronghold of his Justice and Development Party.
"I say this very clearly: either Taksim Square is cleared, or if it isn't cleared then the security forces of this country will know how to clear it," Erdogan said.
A second pro-government rally is planned for Sunday in Istanbul, though Erdogan has previously said that the rallies were not designed as "an alternative" to the demonstrations at Gezi Park, but part of early campaigning for local elections next March.
On Saturday, Erdogan lashed out at what he called the "plot" behind the biggest street protests in his 10-year tenure.
"Over the last 17 days, I know that in all corners of Turkey, millions and billions have prayed for us," Erdogan said, as he moved about the stage. "You saw the plot that was being carried out, the trap being set." He said his supporters represented the "silent masses."
"You are here, and you are spoiling the treacherous plot, the treacherous attack!" he said, insisting unspecified groups both inside and outside Turkey had conspired to mount the protests centered on Istanbul ? and that he had the documents to prove it.
The crowd chanted in response: "Stand straight, don't bow, the people are with you!"
In his speech, he focused on some protesters who have clashed with police ? at time by throwing stones and firebombs.
"There is no breaking and burning here, we are people of love," Erdogan said. "If people want to see the real Turkey, they should come here to Sincan,"
Erdogan already has offered to defer to a court ruling on the legality of the government's contested park redevelopment plan, and floated the possibility of a referendum on it. But concessions over the park seemed not to be enough.
Earlier this week, Erdogan ordered Taksim Square to be cleared of protesters. Police moved past improvised barricades on Tuesday, firing tear gas and rubber bullets and using water cannons to fend off small groups of demonstrators throwing stones, bottles and firebombs. Tear gas was also fired through the trees into the park, although the protesters were not removed.
Taksim Square itself returned to normal right after the end of the police operation early Wednesday. Traffic returned, the protest banners and flags were taken down, and cafes set up their chairs and tables outside again. At night, demonstrators still spill out from the park down the steps, while riot police kept watch from the edges.
Kahraman, the member of the Taksim Solidarity group who met with Erdogan in last-ditch talks that lasted until the pre-dawn hours Friday, said the protesters had agreed to continue their sit-in at Gezi Park after holding a series of discussions.
"We shall remain in the park until all of our democratic rights are recognized," he told The Associated Press earlier Saturday, insisting that four key demands laid out by protesters in the talks had not been met.
The group has demanded that the park be left intact, anyone responsible for excessive police force resign or be fired, all activists detained in the protests be released, and the police use of tear gas and other non-lethal weapons be banned.
According to the government's redevelopment plan for Taksim Square that caused the sit-in, the park would be replaced with a replica Ottoman-era barracks. Under initial plans, the construction would have housed a shopping mall, though that has since been amended to the possibility of an opera house, a theater and a museum with cafes.
Earlier Saturday, President Abdullah Gul wrote on Twitter that "everyone should now return home," insisting that "the channels for discussion and dialogue" have opened ? an apparent reference to the talks between Erdogan and a small group of delegates from the protest.
___
Keaten reported from Ankara, Turkey. Suzan Fraser in Ankara, Turkey, contributed to this report.
Source: http://news.yahoo.com/riot-police-disperse-protesters-istanbul-park-190240032.html
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Saturday, June 15, 2013
Key mechanism boosts the signaling function of neurons in brain
June 14, 2013 ? Locating a car that's blowing its horn in heavy traffic, channel-hopping between football and a thriller on TV without losing the plot, and not forgetting the start of a sentence by the time we have read to the end -- we consider all of these to be normal everyday functions. They enable us to react to fast-changing circumstances and to carry out even complex activities correctly. For this to work, the neuron circuits in our brain have to be very flexible. Scientists working under the leadership of neurobiologists Nils Brose and Erwin Neher at the Max Planck Institutes of Experimental Medicine and Biophysical Chemistry in G?ttingen have now discovered an important molecular mechanism that turns neurons into true masters of adaptation.
Neurons communicate with each other by means of specialised cell-to-cell contacts called synapses. First, an emitting neuron is excited and discharges chemical messengers known as neurotransmitters. These signal molecules then reach the receiving cell and influence its activation state. The transmitter discharge process is highly complex and strongly regulated. Its protagonists are synaptic vesicles, small blisters surrounded by a membrane, which are loaded with neurotransmitters and release them by fusing with the cell membrane. In order to be able to respond to stimulation at any time by releasing transmitters, a neuron must have a certain amount of vesicles ready to go at each of its synapses. Brose has been studying the molecular foundations of this stockpiling for years.
The problem is not merely academic. "The number of immediately releasable vesicles at a synapse determines its reliability," explains Brose. "If there are too few and they are replenished too slowly, the corresponding synapse becomes tired very quickly in conditions of repeated activation. The opposite applies when a synapse can quickly top up its immediately available vesicles under pressure. In fact, such a synapse may even improve with constant activation."
This synaptic adaptability can be observed in practically all neurons. It is known as short-term plasticity and is indispensable for a large number of extremely important brain processes. Without it, we would not be able to localise sounds, mental maths would be impossible, and the speed and flexibility with which we can alter our behaviour and turn our attention to new goals would be lost.
Some years ago, Brose and his team discovered a protein with the cryptic name of Munc13. Not only is this protein indispensable for the replenishment of vesicles for immediate release at synapses; neuron activity regulates it in such a way that the fresh supply of vesicles can be adjusted in line with demand. This regulation occurs by means of a complex consisting of the signal protein calmodulin and calcium ions that build up in the synapses during intense neuron activity.
"Our earlier work on individual neurons in culture dishes showed that the calcium-calmodulin complex activates Munc13 and consequently ensures that immediately releasable vesicles are replenished faster," says Noa Lipstein, an Israeli guest scientist in Brose's lab. "But many colleagues were not convinced that this process also played a role in neurons in the intact brain."
So Lipstein and her Japanese colleague Takeshi Sakaba created a mutant mouse with genetically altered Munc13 proteins that could not be activated by calcium-calmodulin complexes. The two neurophysiologists first studied the effects of this genetic manipulation on synapses involved in the localisation of sound, which are typically activated several hundred times every second. "Our study shows that the sustained efficiency of synapses in intact neuron networks is critically dependent on the activation of Munc13 by calcium-calmodulin complexes," explains Lipstein.
The G?ttingen-based scientists are convinced of the significance of their study. After all, leading neuroscientists of the past described the calcium sensor responsible for synaptic short-term plasticity and its target protein as the Holy Grail. "I am confident that we have discovered a key molecular mechanism of short-term plasticity that plays a role in all synapses in the brain, and not only in cultivated neurons, as many colleagues believed," affirms Lipstein. And if she is, in fact, proved right about the interpretation of her findings, Munc13 could even be an ideal pharmacological target for drugs that influence brain function.
Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/top_science/~3/pNO3ARGqRxk/130614082504.htm
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Friday, June 14, 2013
Sharing a link from Dropbox just got a little easier and faster.
Sharing a link from Dropbox just got a little easier and faster. Now, when you right-click to share, you'll see a "Share Dropbox Link" that will generate and automatically save said link to your clipboard. Neat. [Dropbox]
Source: http://gizmodo.com/sharing-a-link-from-dropbox-just-got-a-little-easier-an-513189471
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Saturday, June 8, 2013
A Complete Visual History of Superman's Signature 'S'
The premier of Man of Steel
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Airbus Bag2Go smart luggage wields GPS, RFID to skip airport hassles
Many of us avoid flying with checked baggage when possible, and for good reason: even a simple delay can sour a whole trip. Airbus' new Bag2Go prototype could save us from having to pack light, however. The smart luggage carries a raft of sensors that work with an iOS app to bypass the usual airport drudgery. Its RFID chip lets travelers check in their bag and link it to every step of their itinerary; in theory, couriers can ship baggage to the hotel at a lower cost than usual. Bag2Go should also provide some reassurance through GPS tracking and alerts to any possible tampering. Airbus is still early into development, but it foresees a business model where customers can either buy a Bag2Go suitcase at a premium or rent one for a long vacation. As for us? We'll just be happy if our luggage avoids an unexpected detour to Belize.
Filed under: GPS, Transportation
Via: MacRumors, Australian Business Traveller
Source: Design Q (Vimeo)
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